British Society for Research on Ageing

Signal Transduction is broadly defined as mechanisms of information exchange between different biological compartments.  As such, signal transduction mechanisms have provided crucial insights into the workings of biological systems.  Signal transduction in the cardiovascular system is studied at molecular, cellular and organ system levels.  In addition to the classical endocrine, paracrine and autocrine modes of signaling, cardiovascular cells participate and respond to mechanical, gaseous, and solid state signals.  Although reductionist approaches and pathway analyses have provided critical insights, more comprehensive and quantitative approaches are needed in the ‘-omics’ era in which large data sets are available from molecular profiling studies at the levels of genes, proteins and small molecules. This NAVBO workshop aims to:

-         Highlight recent advances and breakthroughs in signal transduction research

-         Promote the exchange of breakthroughs in signaling research between cardiovascular and other fields

-         Facilitate discussion of classical approaches in signal transduction research with those of emerging approaches such as systems biology and quantitative cell biology.