British Society for Research on Ageing

Day 1: Thursday 17^th July

09.30 - 10.00   Registration and coffee

10.00 - 10.10   Introduction and welcome: Anne McArdle, Chair of BSRA

10.10 - 11.00   Plenary: Janet Lord, University of Birmingham. Dealing with Immune Frailty

Session I

Ageing Tissues

Chair: Joseph Kwan

11.00 - 11.30   Steve Allen. The Royal Bournemouth Hospital and University of Bournemouth. Age-related changes in respiratory sensory function; implications for clinical practice

11.30 - 11.50   Richard Ferguson (SPARC Speaker). Loughborough University. Age-related changes in muscle performance

11.50 - 12.10   Michael Wormstone (SPARC Speaker). University of East Anglia. Age-related signalling capacities of the human lens

12.10 - 13.30   Lunch and informal poster viewing

Session II

Cellular Senescence

Chair: Richard Faragher

13.30 - 14.00   Calvin Harley, Geron Corporation, USA. Cellular Senescence, Telomerase and Ageing

14.00 - 14.30   Thomas von Zglinicki. University of Newcastle Mitochondria and telomeres: strange bedfellows in cell senescence

14.30 - 15.00   Update on BBSRC-NIA Funding Initiative, Richard Faragher

15.00 - 15.30   Afternoon Tea

Session III

Model Systems

Chair: Aphrodite Vasilaki

15.30 - 16.00   Ian Kill, Brunel University. Hutchinson Guilford Progeria.

16.00 - 16.30   David Gems, University College London. Disparate effects of five superoxide dismutases on development, stress resistance and ageing in the nematode Caenorhabditis elegans

16.30 -17.30    Cohen Medal Award and Lecture

Arlan Richardson, South Texas Veterans Health Care and University of Texas Health Science Center at San Antonio, USA

Is the Oxidative Stress Theory of Aging Dead?

19.00 - 20.00   Wine reception and formal poster viewing

20.00 - Late     Conference Dinner

Day 2: Friday 18^th July

09.00 - 10.00   Plenary: Robert Arking. Wayne State University. Multiple Mechanisms of Health Span Extension in Drosophila.

Session IV

Molecular Aspects of Ageing: Cardiovascular fitness

Chair: Janet Lord

10.00 - 10.20   Matthew Lancaster (SPARC Speaker). University of Leeds.  Ageing, exercise and gender

10.20 - 10.40   Andrew Trafford (SPARC Speaker). University of Manchester.  Cardiovascular Ageing - a conundrum of muscle and vessel biology

10.40 - 11.10   Coffee

Session V

Molecular Aspects of Ageing: Analysis of damage

Chair: Lizzy Ostler

11.10 - 11.40   Enrique Cadenas. University of Southern California, USA. Mitochondrial bioenergetics and free radicals in aging and neurodegeneration

11.40 - 12.10   Paul Thornalley. University of Warwick. Chemical analysis of glycation

12.10 - 12.40   Kelvin Davies. University of Southern California, USA. Oxidative damage and the proteasome

12.40 - 14.10   Lunch and informal poster viewing

Session VI

Selected Oral Presentations

Chair: Sian Henson

14.10 - 14.30   Jos Bosch, University of Birmingham UK and Mannheim Institute for Public Health, Social and Preventive Medicine, University of Heidelberg, Germany. Adverse working conditions are associated with CD8+ T cell differentiation indicative of immunosenescence

14.30 - 14.50   Diana Jurk. Centre for Integrated Systems Biology of Ageing and Nutrition, Institute for Ageing and Health, Newcastle University, UK. Role of fibrosis and senescence in ageing mice liver

14.50 - 15.10   N. Minois. Research Institute of Molecular Pathology, Vienna, Austria and Institute of Molecular Biotechnology, Vienna, Austria. New genes extending longevity by RNAi in adult Drosophila melanogaster

15.10 - 15.30   David Melzer. Genetics of Ageing Group, Peninsula Medical School, Exeter UK. Genes for successful ageing in humans

15.30 - 16.00   Afternoon Tea

Closing Session

Psychological Aspects of Ageing

Chair: Anne McArdle

16.00 - 17.00 Chris Moulin, University of Leeds. Memory and Ageing: Selves and Brains

17.00 - 17.15 Prize giving and closing remarks: Anne McArdle