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The University of Manchester - Medical & Human Sciences

Research Associate – quantifying age-related changes in tissue structure and function

The University of Manchester is seeking high quality candidates for two positions that have arisen as a result of an MRC-led Lifelong Health and Wellbeing award made to the Schools of Biomedicine and Translational Medicine (FMHS) and to the School of Materials (FEPS).  This post (based in the School of Biomedicine) will work in close collaboration with the post based in the School of Materials.

Members who are also members of the AAAS might like to look at a blog article there entitled "Can Aging be Overcome", featuring links to TED presentations by Dan Buettner, Aubrey de Grey and Cynthia Kenyon.

Transposon-Mediated Transgenesis in the Short-Lived African Killifish Nothobranchius furzeri, a Vertebrate Model for Aging [Papers of Interest]

According to wikipedia, there are over 1200 species of killifish - these species are distributed through the Americas, southern Europe, Africa and eastern Asia. Nothobranchius furzeri  is an African species with quite diverse colouration patterns (which presumably explains the apparent contradiction between the image here and the species' common name: the Turquoise killifish), and is quite popular as an aquarium fish.  Killifish are particularly short-lived fish, an adaptation to their habitat in transient water bodies.  For the same reason, their eggs are quite resistent to drying out - killiish can be exchanged between labs quite readily as eggs (without water) through the post.  This paper desribes a technique for transgenic modification in killifish, an essential development if killifish is to acquire widespread acceptance as an experimental model organism.

From Papers of Interest - Jennifer Couzin-Frankel (2011) Aging Genes: The Sirtuin Story Unravels Science Vol. 334 no. 6060 pp. 1194-1198 DOI: 10.1126/science.334.6060.1194

From the perspective of a relative outsider to the sirtuin field, this News Item in a recent issue of Science is quite timely, bringing a concise overview of the state of play in the field of Sir2 and its role in the modulation of lifespan. It's an intriguing tale of scientific investigation.  And from a more personal perspective, avoiding complications due to genetic background when analysing the impact of genetic interventions using transgenic Drosophila has been important in my ow research.

The 2012 “Intensive course on Ageing” will be organized in Barcelona, Spain (June 21 and 22, 2012) under the auspices of the IAGG (International Association of Gerontology and Geriatrics). Internationally recognized specialists will share their knowledge on topics on main aspects of social gerontology, biological aging, clinical gerontology.

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Lancaster University Centre for Ageing Research

The emphasis of this international conference is the interdisciplinarity of ageing research. It aims to offer greater understandings of the range of issues recognised by those working on issues of ageing and older people. It will contribute insights from across disciplines in order to move beyond traditional disciplinary boundaries by exploring common strategies and solutions in the following areas:

2012 Buck Symposium - Novato, California

STEM CELL RESEARCH AND AGING

March 1-2, 2012

Visit the Symposium website for further information

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The Genetic, Epigenetic, Inflammatory, and Metabolic Origins of Aging

February 12-17, 2012
Ventura Beach Marriott
Ventura, CA

Chairs:
Nir Barzilai, James L. Kirkland & Heidi Scrable

Vice Chairs:
Pankaj Kapahi & Nektarios Tavernarakis

Visit the Gordon Conference website for further information

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